SPHeRE Blog

Engaging families in community-based childhood weight management programmes

Childhood obesity is a significant public health issue worldwide (1, 2). The current plateau is unacceptably high (3) and the consequences for children, their families and the health service remain substantial(4). Uncertainty surrounds the most effective way to manage childhood obesity in the community (5). While international recommendations agree that […]

Medication Screening of Older Hospitalised Patients: The Cost-Effective Way Forward

Older people often have multiple comorbidities and as a result, are commonly prescribed several drugs. This increases their risk of adverse drug reactions (ADRs).(1) A recent randomised controlled trial conducted in an Irish University teaching hospital that evaluated a physician-implemented medication screening tool, demonstrated positive outcomes in terms of a […]

Optimising exercise prescription to support muscle function in healthy ageing

We are currently in the midst of unprecedented shifts in population age profile, which underscore the need for strategies that promote healthy ageing. For instance, the number of people aged over 60 years has tripled since 1950, reaching 605 million in 2000, and will double that to 1.2 billion in […]

Participants’ Perspectives and Preferences on Clinical Trial Result Dissemination: The TRUST Thyroid Trial Experience.

The results of clinical trials are not traditionally disseminated to clinical trial participants. While there is a growing awareness that participants should receive study results, little is known about the most appropriate methods of doing so. The Thyroid Hormone Replacement for Subclinical Hypothyroidism Trial (TRUST) was a multi-centre, double-blind, randomised, […]

Patients, Placebos, and Clinical Research: Making much ado about nothing

Researchers are required to furnish patients with information to enable them to make informed decisions. In medical research participants need to know: “What are the risks of participating? What are the risks of not participating? What are the possible benefits?” Providing this information is an ethical imperative. Studies show that […]

Lifestyle Approaches to Cholesterol Management

Cardiovascular disease (CVD) remains the leading cause of premature death and disability worldwide [1]. In Ireland, approximately 10,000 people die each year from CVD – including coronary heart disease (CHD), stroke and other circulatory diseases. While it is not possible to change the non-modifiable risk factors for CVD (such as age, ethnic background and […]